Tissue Repair, Contraction and the Myofibroblast

Tissue Repair, Contraction and the Myofibroblast

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Tissue Repair, Contraction and the Myofibroblast summarizes the most recent findings concerning the biology of the myofibroblast, a cell involved in the evolution and contraction of granulation tissue and of fibrotic changes. This recent work shows that the myofibroblast is responsible for the development of pathological situations such as hypertrophic scars, pulmonary and renal fibrosis and bronchial asthma.Mechanical forces are central to the control of 3D spatial organisation in connective tissue remodelling, repair and scarring. ... We take for granted their repair and even fibrosis after injury and their ability to withstand the habitual mechanicalanbsp;...

Title:Tissue Repair, Contraction and the Myofibroblast
Author: Christine Chaponnier, Alexis Desmoulière, Giulio Gabbiani
Publisher:Springer Science & Business Media - 2007-02-26

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